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Most adverse events reported with topical GHK-Cu are limited to localized redness, tingling, or irritation
Requires medical supervision dose escalation and side-effect monitoring are essential
Additionally, other medications commonly used in patients with metabolic disorders may contribute to sexual dysfunction, including certain antihypertensives (especially thiazide diuretics and beta-blockers), antidepressants (particularly SSRIs), 5-alpha-reductase inhibitors, and opioid analgesics
Liraglutide (Saxenda) NICE Technology Appraisal TA664 recommends liraglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, within a specialist weight management service
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