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The nasal spray format was not chosen for convenience, but for its utility in modeling alternative delivery pathways - especially in metabolic or neuroendocrine research scenarios

Allergic reactions : Symptoms such as severe swelling, rash, or difficulty breathing require immediate medical attention

The index date for the case group was defined as the date of the first tirzepatide prescription, while for the control group, it was the date of the first prescription for one of the aforementioned anti-obesity medications