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Notably, 1 O exihibits a high degree of chemical reactivity, allowing it to directly target lipids, proteins, and DNA in cell membranes, thereby inducing oxidative damage [88]
It interacts with DNA to form adductssuch as DNADNA and DNAproteins crosslinkswhich activate several signal transduction pathways that trigger cell death 74,76
43,44 To assess whether TRIM37 directly ubiquitinates TRIM28, we performed in vitro ubiquitination reactions
Oral BPC-157 is designed to act locally within the gastrointestinal tract, which makes it more appropriate for gut applications than systemic injection
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