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The single most important practical distinction among these peptides is the route of administration , because it largely determines both the evidence base and the risk profile

Recent advancements in the nano-encapsulation of curcumin have established a method to enhance its stability and solubility in aqueous environments, facilitating its delivery to various cellular compartments, particularly inner ear cells, that are primarily affected by cisplatin ototoxicity (Aggarwal and Sung 2009