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Engineering peptide-antibody fusion molecules with reduced GLP-1R potency Dose dependent gastrointestinal adverse events are well-known effects associated with GLP-1 therapy 18

Even though current evidence suggests GLP-1 medications do not show an increased risk of suicidal thoughts or behaviors when used as prescribed, individuals should report any mood changes to their healthcare provider

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Without alternative diabetes management strategies in place, this can result in hyperglycaemia, with symptoms including increased thirst, frequent urination, fatigue, and blurred vision