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For example, the BNF notes that pancreatin can reduce the effect of acarbose (an antidiabetic medication) [13] [14] Allergic reactions : Many products are derived from animal (often porcine) or fungal sources and may trigger sensitivities or have religious implications Gastrointestinal irritation : High-dose enzyme supplements may worsen nausea or abdominal discomfort in some individuals Masking underlying conditions : Self-treating with supplements may delay diagnosis of serious digestive disorders Before purchasing any supplement, check the ingredient list carefully for allergens and avoid products making exaggerated health claims

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Tirzepatide is a once weekly subcutaneous injection