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doi:10.1111/dom.13624 Flint A, et al

Carnitine is an amino acid derivative (a building block of protein) made by the body in the liver, kidneys and brain, from two other amino acids, lysine and methionine

Second, it enables researchers and practitioners to identify individual tolerance thresholds before reaching maximum doses

The objective was to avoid any negative impact of the amino urea side chains on the potency so the observed activity would correlate the loss of affinity predicted from the Ala scan (Table 1 and Fig