Arch Biochem Biophys 237:408414 Cadenas E, Boveris A, Ragan CI, Stoppani AO (1977) Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
doi: 10.3390/cancers14010112 35 HsuSPCChenY-CChiangH-CHuangY-CHuangC-CWangH-Eet al
It is essential to approach these interventions with caution, considering individual differences and the intricate balance of potential benefits against nutritional deficiencies or other risks
Assuming a sequential reaction, where the enzyme, GPX, must bind to both substrates, ROS and GSH, for the reaction producing GSSG to occur and letting ROS and GSH to be the leading and following substrates, respectively, is the the reaction rate for GSSG