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When the target area is the double chin or the back of the upper arm, the anatomical fat thickness is significantly reduced

Not only has the Food and Drug Administration (FDA) fielded thousands of complaints tied to less expensive, compounded versions, but a 2026 Yale secret-shopper study found many online sellers of affordable GLP-1 drugs skip basic safety steps before prescribing

Improvements in blood glucose and lipid parameters were also observed in trial settings

Rothenhoefer had been testing a drug, sold by pharmaceutical company Eli Lilly, which later won FDA approval for weight loss in 2023 under the brand name Zepbound