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Nat Struct Mol Biol
GLP-1 RAs might give a person with BED respite from the cycle, while giving them skills, and having a planned taper off the medication at the end. She shared an anecdote of a patient with BED who had been taking a GLP-1 RA, who was happy with their weight loss and no longer snacked, ate excessively, or consumed high-fat and high-sugar foods
Some data suggest potential neuroprotective effects of LIRA and SEMA in neurodegenerative diseases,34 through various mechanisms possibly related to improved insulin sensitivity, anti-inflammatory actions, and inhibition of oxidative stress, mediated by GLP-1 receptors also present in astrocytes and microglia
Lilly describes these events as generally mild to moderate with the majority resolving during treatment
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