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In March 2023, Zavegepant nasal spray received its first approval in the USA for the acute treatment of migraine with or without aura in adults
Outcomes assessed at initiation, six months and discontinuation or last consultation included HS-PGA, flare frequency, Numerical Rating Scale (NRS) for pain and suppuration, Dermatology Life Quality Index (DLQI) and body mass index (BMI)
Dose-Pause and Discontinuation Patterns Trial protocols paused dosing for protocol-defined adverse events
You need to understand your vial concentration, calculate correct injection volumes, and practice proper reconstitution techniques if working with lyophilized powder
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