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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

[4] Some individuals might experience mild diarrhea or gastrointestinal upset after parenteral B-vitamin administration

Whilst some patients report increased energy within 4872 hours, others may not notice significant changes for several weeks

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