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however, this is not currently listed as a class contraindication in UK Summaries of Product Characteristics (SmPCs) for licensed GLP-1 receptor agonists, and patients should not assume a blanket prohibition applies
The weight loss and insulin sensitivity improvements associated with orforglipron would be expected to significantly reduce the risk of progression from prediabetes to overt type 2 diabetes
Maintaining Your Results: Long-Term Success Once you reach your maintenance dose, the focus shifts to sustaining results and supporting long-term wellness
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