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Dermatology research and practice, 2020, 8547960
The comparator groups differed among studies, with some employing placebo controls (e.g., PIONEER-6, Gerstein 2019), others using active comparators such as sitagliptin, glimepiride, DPP-4 inhibitors, or SGLT2 inhibitors, and some utilizing standard care or intensive lifestyle interventions as the control
Weight from fluid retention may resolve quickly, while actual fat gain or the distinctive "moon face" and fat redistribution, particularly in the abdomen, takes longer to reverse
As low dose of ferroptosis-inducing agents mimics the effects of gpx-3(tm2059) , gpx-5(tm2024) and gpx-8(tm2108) mutations, while high dose mimics the effects of gpx-1(tm2100) and gpx-4(tm2111) mutations, its possible that loss of GPX-3, GPX-5 or GPX-8 leads to a low level of lipid oxidation, and loss of GPX-1 or GPX-4 causes a higher level of lipid oxidation
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