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Nonetheless, some commercial mimics of GLP-1, such as Liraglutide, even when administered peripherally, appear to cross the BBB and activate neurons within the ARC resulting in GABA dependent inhibition of neuropeptide Y (NPY) and agouti-related peptide (AgRP) secretion
Specifically, it may help reduce the risk of heart attacks, strokes, and other heart disease-related events in people who are overweight or have obesity with heart disease
Therapeutics and Clinical Risk Management, 7 , 377385
Compounded meds should only be considered when there is a national drug shortage, and no approved product is available
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