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Under appropriate steady-state conditions, values closer to 0.7 are associated with a greater relative contribution from fat oxidation, whereas values closer to 1.0 are associated with a greater relative contribution from carbohydrate oxidation
It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease
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