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Massive paracetamol ingestion 30g or 500mg/kg or paracetamol concentration double the nomogram line Patients who have a paracetamol concentration greater than double the 150mg/L at 4 h nomogram line have an increased risk of hepatotoxicity

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4 Complementary central nervous system action Amylin receptor signalling in the brain works through different neural circuits than GLP-1 receptor signalling