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In this context, increased expression of detoxifying enzymes may lead to the development of redox adaptative mechanisms that could perturb cell homeostasis and even promote leukemic transformation
As with all supplements, some people should avoid milk thistle altogether, primarily individuals who are allergic or sensitive to Asteraceae and/or Compositae plants and those currently on medications that may severely interact with silymarin (e.g., deferiprone or simeprevir)
The presence of microplastics may potentially harm the central nervous system by affecting neuronal function and survival through multiple mechanisms, including neuroinflammation, oxidative stress, cytotoxicity, and hormonal disruption (3)
The challenge is knowing which signals matter, and which ones dont
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