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Gastrointestinal side effects: Nausea, vomiting, and diarrhoea which are frequently reported in trial data can lead to dehydration and electrolyte imbalances, both of which may contribute to fatigue

In rheumatoid arthritis (RA), overproduction of the cytokine tumor necrosis factor (TNF) is a central event in pathogenesis, and endoplasmic reticulum (ER) rich T cells are the major releasers of TNF in inflamed joints

The impact of a single missed injection is typically mild compared to stopping treatment entirely

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