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It was observed that the treatment of rats on a high-fat diet with exendin-4 resulted in a decrease in the number of osteoclasts and the area of eroded surfaces, while there was an increase in the osteoid area, bone mass, and trabecular bone volume

The amber color protects the light-sensitive nutrient to extend its useful life

These combined actions have led to interest in its relevance for research models involving cardiovascular stress and impaired circulation.(23) Further animal-based investigations have reported protective effects in models of cardiac injury

The interest has helped fuel a grey market where consumers seek access to research-grade injections, including experimental weight-loss therapies such as retatrutide