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Wang, F., Chen, F., Cai, Y., Zhang, G

Nevertheless, the improvement in lipid tolerance was similar in mice receiving the 2 different doses of sitagliptin (Figure 1C), highlighting the importance of DPP-4 + cells within the gut for control of lipid tolerance

For Biomarker Research, the most promising direction is not a single universal metabolite but a phenotype-aware, pathway-anchored biomarker strategy that integrates circulating metabolites with imaging, clinical context, and validated outcomes

the non-enzymatic pathway involves ROS and Fe 2+ -driven Fenton reactions, which induce spontaneous oxidation of PUFA-PLs and further accumulation of PUFA-PL-OOHs (Kwun and Lee, 2023)