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Ele desempenha um papel crucial na regulao dos nveis de glicose no sangue, estimulando a secreo de insulina e inibindo o glucagon, outro hormnio que eleva a glicose sangunea
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While semaglutide GLP-1 is highly effective, it is important to address potential gastrointestinal side effects, such as nausea and diarrhea, which are generally transient and manageable
Phase 2 results at 48 weeks (Jastreboff et al., NEJM 2023): Phase 3 TRIUMPH-4 at 68 weeks (Lilly Press Release, Dec 2025): The 12 mg dose produced 28.7% body weight loss, an average of 71.2 lbs from a 248.5 lb baseline
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