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Our program is built around prescription GLP-1 medications like Ozempic (semaglutide) and Zepbound (tirzepatide), available through trusted partners like NovaCare and LillyDirect
This compound serves an essential function in lipid metabolism, particularly facilitating the transport of long-chain fatty acid molecules across the mitochondrial membrane into the matrix, where -oxidation occurs
We also tested a non-CRC model, the osteosarcoma U2OS cell line, which is wild-type for APC, KRAS and p53, and confirmed a similar 5FU-driven change in mitochondrial mass and morphology (Extended Data Fig
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