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(Research has identified mast cells as one of the immune cell types involved in the inflammatory cascades that influence arterial plaque development and lipid-related cardiovascular risk, as I note in my MCAS info page.) In neurological disease , research in animal models of stroke and vascular dementia has shown that GLP-1RAs reduce both microglial activation and neuroinflammation, leading to better protection of the brain from injury and cognitive deterioration
Myocardial fibrosis predicts appropriate device therapy in patients with implantable cardioverter-defibrillators for primary prevention of sudden cardiac death
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10.1038/nm1415 248 NitaIiHershfinkelM.KantorC.RutterG
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