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Improved mood and mental clarity (11-14% of reviews) A subset of the energy-improvement group specifically mentions mood elevation, reduced anxiety, or "mental sharpness." This aligns with B12's role in neurotransmitter synthesis and methylation reactions affecting serotonin and dopamine pathways (Kennedy, Nutrients , 2016)
But some studies on vitamin B12 and bone health have shown mixed results
there have been no reports of organ damage or severe reactions directly linked to NAD+ in clinical studies
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