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It has also been demonstrated that inhibitory GABAergic CNS GIPR + neurons are necessary for the food intake reducing effects of GIPR agonists and dual incretin co-agonists (54, 55), while excitatory glutamatergic CNS GLP-1R + neurons are necessary for the food intake reducing effects of GLP-1R agonists (71)

Finally the weight lost by the group of 1mg dose was slightly more than that achieved by the worlds largest selling prescription obesity medication in similar trials over the same period, without its troublesome side effects

The most common side effect is injection-site soreness (41% of patients, mild, resolving in 24-36 hours)

I recommend doing your oral hygiene routine before applying this, because you want to soak in all its benefits