These changes may also create distributional effects, as some consumers face higher prices than under the status quo, raising equity concerns if lower-income consumers access to affordable protein is strained
"From what I can tell, many people on these highly effective drugs are eating less than a thousand calories a day, some as low as 600 to 800, and that is a level of semi-starvation," says Kessler
Details of the National Institutes of Health-funded study were published this week in a Nature paper titled A brain reward circuit inhibited by next-generation weight-loss drugs in mice. In it, the team reported that they investigated the small-molecule GLP-1s including Eli Lillys recently approved drug orforglipron, also known by the brand name Foundayo, as well as danuglipron, an oral GLP-1 that was being developed by Pfizer until the company decided to discontinue its development in 2025
Through its stimulation of angiogenesis, it promotes the growth of new blood vessels