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Dropout rates were highest in the early titration phases and decreased as individuals moved into the stable maintenance phase

The temporal relationship between starting the medication and symptom onset may suggest an association, but this requires careful clinical evaluation rather than automatic attribution to the drug itself

Still, we read it carefully: as Section 5.8 spells out, the short 2-week washout leaves the drug on board and confounds the rechallenge, so this points toward a doseresponse relationship rather than proving one

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