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Many mild side effects are local and brief, but repeated injections over years are poorly characterized in the literature
There are practical reasons too: B can be unstable if mixed with certain other vitamins in solution, and dosing schedules for B deficiency (pernicious anemia, for instance) may differ
Reconstitution and administration instructions are part of the clinical guidance a provider gives a patient who has been evaluated and prescribed a compound
Severely obese patients may be good candidates as well
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