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severe renal or hepatic impairment
Wiley Interdiscip Rev Nanomed Nanobiotechnol
The hypothesis of post-receptor alterations involved in resistance to SS analogs is supported by the dissociation between the antisecretory and antiproliferative effects of SS analogs observed in vivo in some acromegalic patients and in in vitro experiments in tumoral somatotroph cells where SS analogs exert antiproliferative effects without inhibition of GH secretion (5052)
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