glutathione spike protein

glutathione spike protein deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease Evaluation of Glutathione in Spike

Name: glutathione spike protein deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease Evaluation of Glutathione in Spike
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PMID 40672369

By contrast, under nutrient-depleted or amino acid starvation conditions, intracellular glutathione levels progressively decline, thereby lowering the execution threshold for GPX4 inhibition-induced ferroptosis

We tested several reported inducers of ferroptosis (Fig S5D-F) and while parasite growth was inhibited, these compounds also greatly reduced host cell viability, confounding any possible interpretations of the results