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FDA-approved since 2005, GLP-1 agonists, including exenatide and newer formulations, have shown promise in improving glycemic control and aiding in sustained weight management (7)
A previous study of liraglutide on mice fed a diet lacking methionine and choline also found that GLP-1RAs not only could improve IR, but also reduce harmful ceramide/nerve sheath types, and reduce NAFLD inflammation and fibrosis (191)
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