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Protein S-glutathionylation decreases superoxide/hydrogen peroxide production xanthine oxidoreductase

Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression

In Stxbp1 K98Q knock-in mice, the upregulation of STXBP1 K98cr reduces the binding with syntaxin-1B(STX1B), leading to a decreased assembly of soluble NSF attachment protein receptors (SNAREs) in presynaptic active zone and subsequent inhibition vesicle release, thereby promoting epilepsy formation