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Through comprehensive metabolomics, lipidomics, and proteomics analyses, we identified that the PPAR pathway plays a crucial role in lipid metabolism regulation and the progression of MAFLD
1 GLP-1 is a native hormone that is released in response to food intake and acts as a physiological regulator of appetite 1,2 Saxenda is 97% similar to native GLP-1 1 Saxenda works in the hypothalamus, where it interacts with specific neurons involved in the regulation of appetite and food intake 1,a Saxenda increases feelings of satiety and decreases hunger 3 As a result of its mechanism of action, patients taking Saxenda feel satisfied and eat less food, leading to weight loss 3 a Shown in animal models
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Akkermansia Muciniphila AKK11, Bifidobacterium Infantis BI02
