You're not experimenting with questionable substances
Group 2 (persisters, ~35% of those with early constipation): Constipation is still worsening or unchanged at week 6
Cephalalgia 38(8):14711484 Tamborlane WV, Barrientos-Prez M, Fainberg U, Frimer-Larsen H, Hafez M, Hale PM, Jalaludin MY, Kovarenko M, Libman I, Lynch JL, Rao P, Shehadeh N, Turan S, Weghuber D, Barrett T (2019) Liraglutide in Children and Adolescents with Type 2 Diabetes
Decrease in wound tensile strength following post-surgical estrogen replacement therapy in ovariectomized rats during the early phase of healing is mediated via ER-alpha rather than ER-beta: a preliminary report