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In another recent larger but uncontrolled prospective study in gastroparesis [81], at 12 months symptoms had improved in 56% of participants who underwent G-POEM and gastric emptying, measured by scintigraphy, normalised in 47% with a moderate correlation between symptom improvement and acceleration of gastric emptying [81]
Overall, C3G stimulates GLP-1 secretion from intestinal L cells via this pathway, indirectly boosting insulin release from cells
Bootz, A
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