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Because wide spread use of these weight loss drugs is quite new there arent many large studies

It produces and recycles cerebral spinal fluid, similar to the way the kidneys act as a filter for the rest of the body

doi: 10.1038/nn.3871 211 HellerEAHamiltonPJBurekDDLombrosoSIPeaCJNeveRLet al

Wegovy is specifically FDA-approved for chronic weight management in adults and adolescents aged 12 years and older with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes, dyslipidemia) [8] [9]