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What are the side effects I should actually worry about

Consistent with this, exogenous -KG supplementation can enhance Arg1 expression and suppress iNOS expression, and changes in metabolic ratios such as -KG/succinate are closely associated with the activation of M2-related transcriptional programs ( It should be noted that the effects of Gln metabolism on polarization direction are markedly context-dependent

However, if you have kidney issues or take other medications, its smart to talk to your healthcare provider before starting any new supplement