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This gradual titration helps minimise gastrointestinal side effects, which are common with GLP-1 receptor agonists

In mice suffering from non - alcoholic fatty liver disease (NAFLD), liraglutide significantly elevated the abundance of Akkermansia , Romboutsia , and specific members of Bacteroidales, while reducing that of Klebsiella , Anaerotruncus , Bacteroides , and several taxa within the Lachnospiraceae and Ruminococcaceae families ( Firmicutes (e.g., Lachnospiraceae , Clostridiales ) and increased beneficial taxa like Verrucomicrobia and Oscillospiraceae (Madsen et al., 2019)

Instead, NAC is used to provide cysteine in a stable supplement form

not indexed in PubMed as of July 2026)