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It acts as a non-selective agonist at MC1R, MC3R, MC4R, and MC5R, with particularly high potency at MC1R, the receptor governing melanogenesis in epidermal melanocytes
Longer studies and real-world evidence collected through registries are essential
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Analysis of calcium ion (Ca 2+ ) levels in macrophages To detect the intracellular Ca 2+ content, 143B cells were incubated with PBS, Ru(II)-OH, NP2, and NP4 (Ru 10 M) for 6 h
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