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On the heart and circulation, the Phase 2 data show consistent reductions in resting blood pressure of approximately 5 to 8 mmHg at the higher doses, alongside large improvements in the cholesterol pattern most associated with heart disease
Marathe, et
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106,107 Unlike siRNA-mediated gene silencing, miRNAs can simultaneously recognize and regulate the expression of multiple target mRNAs due to their low complementarity
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