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Although the human body can produce glutathione on its own, production can have difficulty keeping up in times of excess stress, immune challenges, unhealthy microbial environments, or during aging, as glutathione status can decline with the natural aging process

doi:10.1111/j.1468-2982.2007.01270.x

Factors Affecting Individual Dosage Requirements Even though 1000 mcg is the usual dose, some people might need more or less