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The small tetrapeptide size (~390 Da) makes Epithalon subject to rapid enzymatic cleavage and renal clearance
The limitations of the study included the pretreatment following the use of ASE, which indicate preventive effect only and not sure about the possible treatment and/or extrapolation on the inflammatory processes
use within 12 weeks with bacteriostatic water preservative [7]
In WT mice, both Cagrilintide and sCT significantly increased cFos expression in these hindbrain nuclei compared to vehicles, indicating activation of satiety-related pathways
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