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A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis

The Perfect B protocol doses MOTS-c at 5mg (25 units) per injection, once every 5 days, for a total of 4 injections over a 20-day cycle

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Mechanistic pathways identified in animal and in vitro work include: FAK-paxillin pathway activation: BPC-157 stimulates focal adhesion kinase (FAK) and its downstream effectors, promoting fibroblast migration and tendon cell outgrowth