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How BPC-157 May Work (Preclinical Evidence) Summary: BPC-157 (a 15-amino-acid peptide) shows multi-system activity in animal and in-vitro studies, including effects on angiogenesis, nitric-oxide (NO) signaling, gastro-mucosal integrity, tendon healing pathways, and endothelial function
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Importantly, BPC 157, but not PDGF-BB, stimulated earlier maturation of granulation tissue, soluble collagen concentration in the exudates (using sponge implantation), and organized collagen significantly more in wounds (i.e., on day 12 after daily treatment) (Tkalcevic et al., 2007)
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