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It can suppress autophagy by antagonizing MiT/TFE transcription factors and repressing lysosomal and ATG gene expression but can enhance autophagy under ER stress by activating the PERKeIF2ATF4 signaling pathway to promote autophagy gene induction
1 2 42% of U.S
Redpath, O
All nanoLC-MS/MS experiments were performed on a Orbitrap Exploris 480 (Thermo Scientific) equipped with an Easy n-LC 1200 HPLC system (Thermo Scientific)
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