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doi: 10.3389/fphar.2022.808855 Received 04 November 2021 Accepted 11 February 2022 Published 17 March 2022 Volume 13 - 2022 Edited by Leo A van Grunsven, Vrije University Brussel, Belgium Reviewed by Prasanna K
In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme formsmethylcobalamin and adenosylcobalaminwhich, depending on the pH environment, can interconvert with hydroxocobalamin ( Despite extensive biochemical knowledge of cobalamin metabolism and its physiological importance, the optimal supplementation route for maintaining or restoring adequate vitamin B12 levels remains debated
BioMed Research International, 2015, 648108
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