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Only 26% of patients had been titrated to goal by the primary endpoint at week 30, at which time the mean daily insulin dose was 29 U per day

Por otro lado, promueve de forma directa el desarrollo de ateroesclerosis (3) y desencadena un aumento de las citocinas inflamatorias, especialmente de la interleucina-6, lo que provoca un estado inflamatorio crnico, aumentando la morbilidad y mortalidad por enfermedades cardiovasculares (4)

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3 Individuals with obesity are prone to developing arterial hypertension and, despite intensive antihypertensive regimens, blood pressure (BP) control in people living with obesity remains suboptimal, particularly when compared with those with a body mass index (BMI) in the normal range