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Protective effects of methylsulfonylmethane on hemodynamics and oxidative stress in monocrotaline-induced pulmonary hypertensive rats

doi: 10.1111/j.1524-475X.2008.00440.x 157 ScotlandRSStablesMJMadalliSWatsonPGilroyDW

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Immediate receptor binding (seconds to minutes), intracellular signaling cascade propagation (minutes to hours), gene expression changes (hours to days), protein synthesis and accumulation (days to weeks), cellular and tissue-level effects (weeks to months)