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A reduced incidence of Alzheimers disease was found in patients with type-2 diabetes taking exenatide [36], and a 2010 trial was launched to investigate the effects of exenatide on cognitive performance and clinical progression of Alzheimers disease [37]
Dupre et al also studied the effects of GLP-1 on glucagon suppression by administering exenatide to patients with type-1 diabetes
In both conditions, one would hypothesized that the glucose-dependency of GLP-1 is also lost given the lack of functional K ATP channels in the first, and the concomitant hyperglycemia in the second
Weve seen this significantly reduce the likelihood of developing severe heartburn. While medication is often necessary, these additional strategies can help: If youre experiencing persistent heartburn while taking semaglutide, tirzepatide, or another GLP-1 medication, its important to discuss your symptoms with your healthcare provider
